Bioengineering and Biomedical Research Group
Contact: Dr. Noelle Comolli
![Jacob Elmer, Ph.D.](/content/villanova/engineering/research/bioengineering-biomedical/_jcr_content/pagecontent/trisection_0/image.img.jpg/1689091111993.jpg)
Jacob Elmer, Ph.D.
Optimization of gene delivery and expression for CAR-T cell immunotherapy, with a specific focus on epigenetic control of transgene expression and the innate immune response to non-viral gene delivery. In addition, our lab is also developing earthworm hemoglobin as a novel, safe, and effective substitute for donated blood.
![William J. Kelly, Ph.D.](/content/villanova/engineering/research/bioengineering-biomedical/_jcr_content/pagecontent/trisection_5/image.img.jpg/1658319740484.jpg)
William J. Kelly, Ph.D.
Research: Computational Fluid Dynamic (CFD) modeling of bioprocessing equipment, Fermentation and isolation of DNA plasmids for gene therapy applications, Optimization of CHO cell culture for production of monoclonal antibodies (Mabs), Shear-induced degradation of biological macromolecules and cells
![Rosalind M. Wynne, Ph.D.](/content/villanova/engineering/research/bioengineering-biomedical/_jcr_content/pagecontent/trisection_3/image.img.jpg/1658319782727.jpg)
Rosalind M. Wynne, Ph.D.
Research: Fiber-optic based biomolecular sensors, including microstructured optical fiber (MOF) sensors for DNA sequencing and single-molecule spectroscopy