February 2014: Congratulations to Dr. Aimee Eggler, the recipient of a Cottrell College Science Award from the Research Corporation for Science Advancement! The focus of the work is the "Activation of the Nrf2 pathway by oxidizable diphenol compounds: Elucidating the contributions of the electrophilic form and reactive oxygen species."
December 2013: Senior Biochemistry major Joana Petrescu has been named Villanova’s first ever Marshall Scholarship winner. Congratulations on this tremendous honor! Joana will use this award to study cancer biology at Cambridge University. Read more about Joana and the Marshall Scholarship!
November 2013: Dr. Daniel Kraut has published an article entitled, “Slippery Substrates Impair ATP-dependent Protease Function by Slowing Unfolding” in the Journal of Biological Chemistry. Check it out! Congratulations!
November 2013: The Wilson lab has published an article entitled, “Engineering large functional plasmids for biosafety” in Plasmid. Congratulations!
August 2013: Dr. Aimee Eggler delivered the PSNA/Elsevier Award Lecture at the 52nd Annual Meeting of the Phytochemical Society of North America. Well done! At the same meeting, graduate student Zachary Kemmerer presented his work entitled, “Synergistic Nrf2/Antioxidant Response Element Pathway Activation by Sulforaphane and Zerumbone through Addition of Redox Catalyst.”
July 2013: Congratulations to the Wykoff lab on their publication in PLos One entitled, “The fate of linear DNA in Saccharomyces cerevisiae and Candida glabrata: the role of homologous and non-homologous end joining.” Kudos!
July 2013: The Palenchar lab presented their work at the Annual Symposium of the Protein Society in Boston, MA.
June 2013: Research from the Selinsky lab on aminosterol antibiotics is published in Bioorganic & Medicinal Chemistry Letters! Congratulations!
June 2013: The Biochemistry program is now offering a Biochemistry minor. You may find the details here.
May 2013: Honors and awards abound for our students!
· Rising senior Biochemistry major Joana Petrescu wins a prestigious Goldwater Fellowship! Rising senior Biochemistry major Daniel Amor receives an honorable mention for the Goldwater Fellowship. Graduating senior Katharine Dynarski also was an honorable mention for the Goldwater last year.
· We proudly have four Phi Beta Kappa inductees this year: graduating senior Lien Trieu and rising seniors Daniel Amor, Jessica Eby, and Joana Prestrecu.
· Graduating senior Katharine Dynarski is the recipient of the Villanova Mendel Medallion in Biochemistry – The Rosalind Franklin Award.
Congratulations to all on these well-deserved honors!
May 2013: Congratulations to our seniors! This year, 21 students graduated in Biochemistry. Of these, one graduated summa cum laude, two graduated magna cum laude, and four graduated cum laude. We wish you all the best in your new endeavors!
May 2013: Kudos to biochemistry students Sarah Mulroy (Eggler lab) and Daniel Amor (Desmond lab)! Both received Villanova Undergraduate Research Fellow (VURF) awards to carry out summer research here at Villanova. Well done!
April 2013: The Villanova Society of Biochemistry and Molecular Biology (VSBMB) is now official! Stay tuned for the happenings of our student biochemistry club.
April 2013: Members of Dr. Angela DiBenedetto’s laboratory presented their work at the regional meeting of the Society for Developmental Biology at the College of William & Mary, Williamsburg, VA:
· Jonathan Rumley, M.S. Biology candidate, presented: Development of a transgenic zebrafish line inducibly overexpressing brd2a.
· Paul Barnett, M.S. Biology candidate, presented: Late centeral nervous system defects and cerebellar-dependent behavioral analysis in transcriptional co-regulator Brd2-knockdown zebrafish larvae.
· Alison Presti, B.S. Biochemistry candidate, presented: Analysis of miRNA expression in Brd2 knock-down zebrafish (Danio rerio) embryos.
· Sydney Lee, B.S. Biology candidate, presented: A PTZ zebrafish kindling paradigm for the study of epilepsy susceptibility.
February 2013: Dr. Barry Selinsky and members of his laboratory attended the Biophysical Society Annual Meeting in Philadelphia. They presented the following work:
· Gassler, F., Tessema, T-D., and Selinsky, B.S., Antimicrobial and lytic activities of squalamine analogs: Effect of varied cationic groups at C3 and stereochemistry at C7, Biophysical Society Annual Meeting, Philadelphia, PA, February 2013.
· Butchy, M.V., Backus, K., Tang, H., and Selinsky, B.S., Cloning, expression, and purification of a putative prostaglandin synthase from Nostoc as a SUMO fusion protein, Biophysical Society Annual Meeting, Philadelphia, PA, February 2013.
January 2013: Dr. Janice Knepper receives a National Institutes of Health AREA/R15 grant to fund her lab’s work on breast cancer! Congratulations!
September 2012: Congratulations to the Wykoff lab on their newest publication in press! Kerwin C.L. & Wykoff DD. 2012 De novo generation of a phosphate regulated promoter in Candida glabrata. FEMS Yeast Research.
August 2012: Dr. Matthew Youngman joins us as a new Assistant Professor of Biology and member of the Biochemistry Program! Dr. Youngman completed his undergraduate work in Biochemistry at Pepperdine University, received a PhD in Cell Biology at the Johns Hopkins University School of Medicine, and carried out postdoctoral work at the Massachusetts Institute of Technology. At Villanova, Dr. Youngman will carry out research to understand the molecular basis for the age-dependent decline in immunity known as "immunosenescence". Using the roundworm Caenorhabditis elegans as a model host, the Youngman Lab will seek to define the mechanisms by which genes that are important for the immune response are regulated during aging and to understand how changes in cellular function that occur later in life impact the ability of an organism to resist infection. Welcome Dr. Youngman!
August 2012: Many congratulations are in order! Dr. Barry Selinsky has accepted the position of Associate Dean for Research and Faculty Development in the College of Arts & Sciences. Dr. Dennis Wykoff has been named the Dennis M. Cook Endowed Gregor Mendel Chair in Genetics. Congratulations to both on these well-deserved honors!
August 2012: Dr. Aimee Eggler is the inaugural recipient of the Phytochemistry/Phytochemical Society of North America Young Investigator Research Grant Award! The award is the first of its kind sponsored by the Elsevier journal Phytochemistry. Congratulations on this honor!
August 2012: Dr. Daniel Kraut and colleagues published the following work: “Sequence- and species-dependence of proteasomal processivity.” Kraut DA, Israeli E, Schrader EK, Patil A, Nakai K, Nanavati D, Inobe T, Matouschek A. ACS Chem Biol. 2012 Aug 17;7(8):1444-53. Congratulations!
August 2012: Our biochemists were well represented at the national meeting of the American Chemical Society in Philadelphia! Posters were presented on “Antimicrobial and lytic activities of squalamine analogs: Effect of stereochemistry at C3 and C7” (T-D Tessema and B.S. Selinsky), “Synthesis and antimicrobial activity of a series of (3β-N-1,3-diaminopropyl) bile acids” (F.G. Gassler and B.S. Selinsky), “PCR and statistical analyses of the observed variations in the CCR5 gene” (F. Raposo, J. Palenchar, B.S. Selinsky, and J. Rucker), “Analysis of amino acid conservation using the functional amino acid navigator” (P. Palenchar), “Unusual cofactor preference of Trypanosoma brucei β-hydroxybutyrate dehydrogenase” (S. Uppal and J. Palenchar), and “Characterization of an essential trypanosome DNA binding protein” (C. Sofa and J. Palenchar)
August 2012: Dr. Jennifer Palenchar has been named the co-director of the Biochemistry program from the Chemistry Department. She joins Dr. Janice Knepper, the co-director from the Biology Department.
August 2012: We sadly inform you of the passing of Dr. Robert Reczkowski. Bob is missed and his many years of teaching and research in the Chemistry Department are greatly appreciated.
July 2012: Members of the Wykoff laboratory attended the Yeast Genetics & Molecular Biology meeting at Princeton University. They presented the following: “De novo generation of a phosphate-starvation regulated promoter in C. glabrata.” (C. Kerwin & D. Wykoff), “Amino acid changes responsible for neofunctionalization of the Candida glabrata PMU2 gene” (K. Orlando, C. Kerwin, M. Cirullo, S. Leone, D. Davies & D. Wykoff), and “Identification of cis regulatory elements in the pho1+ promoter of Schizosaccharomyces pombe.” (M. Peel & D. Wykoff).
March 2012: Dr. Anil Bamezai was invited to speak at the International Conference and Exhibition on Nanotechnology & Nanomedicine, March 12-14, 2012, at Omaha, Nebraska. Title of his talk was: “Nano-structures on plasma membrane of immune cells: isolation and characterization”. Congratulations on this honor!